INTRODUCTION

JONAC contains Diclofenac which belongs to a group of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). It is used to relieve pain, reduce swelling and ease inflammation in conditions affecting the joints, muscles and tendons including rheumatoid arthritis, osteoarthritis, acute gout, ankylosing spondylitis backache, sprains and strains, soft tissue sports injuries, frozen shoulder, dislocations and fractures, tendonitis, tenosynovitis, bursitis. It is also used to treat pain and inflammation associated with dental, minor surgery and juvenile chronic arthritis, also be used alone, or in combination with other painkillers for the short term treatment of pain experienced after an operation (in children).

Diclofenac is an NSAID which exhibits anti-inflammatory analgesic and antipyretic activities. It involves inhibition of cyclooxygenase (COX-1 and COX-2) and it is a potent inhibitor of prostaglandin synthesis in vitro. Diclofenac is an inhibitor of prostaglandin synthesis; its mode of action may be due to a decrease of prostaglandins in peripheral tissues. It used to absorb rapidly into the bloodstream from the rich blood supply of the rectal area. When absorbed, it works by blocking the release of chemical messengers that cause pain and inflammation.

Always use this JONAC exactly as directed by your doctor. Before using this medicine, tell your doctor if you have liver, kidney or heart problems, are pregnant or breastfeeding. Your doctor will prescribe the right dose depends on your age and body weight. The common side effects are nausea, rectal irritation, headache and dizziness.

USES OF JONAC

• Relieves pain, reduce swelling and inflammation in conditions such as rheumatoid arthritis, osteoarthritis, acute gout, ankylosing spondylitis, backache, sprains and strains, soft tissue sports injuries, frozen shoulder, dislocations and fractures, tendonitis, tenosynovitis and bursitis


• Juvenile chronic arthritis (children)


• Also treats pain and inflammation associated with dental and minor surgery

HOW JONAC WORKS

JONAC works by blocking the action of enzyme cyclooxygenase, which is required for the biosynthesis of prostaglandins.

DIRECTIONS FOR USE

Always use JONAC exactly as your doctor has told you. It is for rectum use only and should not take them by mouth.

• Unwrap and insert 1 suppository into the rectum as advised by your doctor


• Lie down on your left side with right knee bent


• Gently push the medicine into the rectum with your finger


• Keep the suppository in the rectum to allow it to melt and the medicine to be absorbed


• Remain lying down for a few minutes, and avoid having a bowel movement for an hour


• Wash your hands after use

SIDE EFFECTS OF JONAC

HOW TO MANAGE SIDE EFFECTS

Nausea:

Stick to simple normal meals and do not eat rich or spicy foods.

Stomach pain:

Place a warm water bottle on your abdomen. Drink plenty of clear fluids and water.

Diarrhoea:

Drink plenty of fluids to avoid dehydration. ORS should be used to prevent dehydration.

Vomiting:

Drink clear or ice-cold drinks. Eat light, bland foods and avoid fried, greasy, or sweet foods.

Dizziness:

Get up and move around to feel awake, take small naps to edge off the sleepiness.

Headache:

Rest and drink plenty of fluids. Apply a cold, wet cloth or ice pack to your forehead. Rest in a quiet, comfortable, dark room.

WARNING & PRECAUTIONS

INTERACTIONS

Inform your doctor if you are using or have recently taken any other medicines, including medicines obtained without a prescription or the following,

• Aspirin or ibuprofen (used for inflammation or pain)


• Warfarin, heparin (used to treat blood clot)


• Medicines to treat diabetes


• Diuretics


• Lithium, serotonin re-uptake inhibitors (used to treat anxiety and depression)


• Phenytoin (used to treat epilepsy)


• Digoxin (used for heart problems)


• Methotrexate, ciclosporin, pemetrexed and tacrolimus (used for inflammation and cancers)


• Quinolones antibiotics (used to treat some infections)


• Steroids (used to treat immune system)


• Colestipol, cholestyramine (used to reduce cholesterol)


• Voriconazole (used to treat fungal infections)


• Mifepristone (used during termination of pregnancy)


• Medicines used to treat heart conditions or high blood pressure (betablockers or ACE inhibitors)

DISCLAIMER

The contents of this website are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please seek the advice of a physician or other qualified health provider with any questions you may have regarding a medical condition. Do not disregard professional medical advice or delay in seeking it because of something you have read on this website.